Rad50 Polyclonal Antibody
簡要描述：Rad50 Polyclonal Antibody宿主: Polyclonal, Rabbit,IgG反應性: Human;Mouse;Rat應用: WB;IHC;IF;ELISA
產(chǎn)品型號： YP-Ab-00509
所屬分類：多克隆抗體
更新時間：2024-11-01
詳細說明：
Rad50 Polyclonal Antibody
抗體，也叫免疫球蛋白（Ig），是一種能特異性結合抗原的糖蛋白，而抗原是在易感染動物體內(nèi)引發(fā)抗體產(chǎn)生的物質(zhì)。在體內(nèi)，抗體是由于外源性分子的侵襲而產(chǎn)生的。抗體以一個或者多個Y字形單體存在，每個Y字形單體由4條多肽鏈組成，包含兩條相同的重鏈和兩條相同的輕鏈。輕鏈和重鏈是根據(jù)它們的分子量大小來命名的。Y字形結構的頂端是可變區(qū)，為抗原結合部位。任何一個抗體的輕鏈都可以分為κ或λ型（基于小分子多肽結構上的差異），每一個抗體的重鏈則決定了它的類或型。
產(chǎn)品詳情
Rad50 Polyclonal Antibody detects endogenous levels of Rad50 protein.
免疫原詳細信息
The antiserum was produced against synthesized peptide derived from human RAD50. AA range:681-730
相關試劑
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
RAD50 double strand break repair protein(RAD50) Homo sapiens The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.[provided by RefSeq, Apr 2010]
天津俊達生物科技有限公司，是從事實驗室耗材銷售的現(xiàn)代化生物科技企業(yè)，公司本著“誠信為本，互利共贏"的核心價值觀，秉承“以市場為導向，提供服務"的宗旨為各大院校、科研單位、第三方實驗室檢測機構等提供的產(chǎn)品和服務。目前公司主要經(jīng)營分子生物學、細胞生物學、免疫學等生物學產(chǎn)品，多種實驗室耗材 歡迎垂詢！
備注：圖片僅供參考。僅供科研，不可用于臨床。
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